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Compared to matched controls, prevalence of platelet-mediated clumping was higher in cases (P = .019), in children presenting with prostration (P = .049) and in children with severe anaemia (P = .025).025
In healthy matched controls, prevalence of Mets was significantly higher and varied from 26.3% (according to the International Diabetes Federation definition) to 30% (according to the AHA/NHLBI definition), as shown in Figure 1 (P ≤0.01 for all comparisons).
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For example, Dickerson et al. compared 149 psychiatric patients with matched controls and found that prevalence of obesity was twice as high as the general US adult population (men 41 vs. 20% and women 50 vs. 27%) [ 1].
Kamen et al. [5] found significantly lower serum 25-hydroxyvitamin D levels among recently diagnosed SLE patients compared to matched controls, and a high overall prevalence of vitamin D deficiency.
Compared with matched controls, which account for the lower prevalence in males, similar risk estimates between relatives to males and female probands were found.
Recently enlisted patients and their matched controls were not found to differ in prevalence of chronic diseases.
After examination by two otolaryngologists, the same children were also shown to have a higher prevalence of middle ear diseases than matched controls (Chao et al. 1997).
The proportions of matched controls with these diseases were similar to their reported prevalence in the general population, 13– 15 suggesting that the control population was reflective of a general population.
The latter prevalence was higher than that found in matched controls (4/103 = 4 %).
As opposed to all previous studies no difference in prevalence of sleep apnea in patients vs. matched controls (38 vs. 34%%, P = 0.64) was identified.
Dyspepsia cases had a higher prevalence of other chronic comorbidities than their matched controls.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com