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A selected animal with elevated anti-gliadin antibodies and a matched control were extensively studied through alternating periods of gluten-free diet and gluten challenge.
Samples from a case and her matched control were always assayed in the same batch.
Only patients with at least one matched control were accepted for the final study set.
A total of 439 pairs of Caucasian women, each pair being 1 RA case and a matched control, were included.
Sera from each case and the matched control were grouped together, and matched sets were randomly organized within batches.
Within the resolution of these assays, no significant differences between two independent sas6l-null lines and the matched control were detected (data not shown).
Similar(53)
The matched control was, therefore, also removed from further analysis.
In addition, a matched control was unavailable for 21 patients.
22 One matched control was selected for each intervention patient.
One patient withdrew for personal reasons; subsequently, the matched control was excluded from analysis.
More well-designed prospective studies, especially with propensity matched control, are needed to solve these limitations.
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