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However, investigating this in future studies is a challenging task given the female preponderance of the disease, and carefully matched control individuals are needed as well.
Fresh-frozen gray matter tissue from dorsolateral prefrontal cortex (Brodmann area 9) of 12 schizophrenia patients and 12 matched control individuals was used in the study.
Clues for mitochondria functions impairment in HIBM were also found previously in genomic expression patterns comparison of muscle specimens from 10 HIBM patients carrying the M712T mutation and presenting mild histological changes, compared with 10 healthy matched control individuals [24].
Mortality was 25%, as compared with 64% for historical matched control individuals.
We then sequenced the variants in a cohort of 170 ethnically matched control individuals (340 chromosomes).
This mutation was excluded in 190 ethnically matched control individuals by restriction digest with BspHI.
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In view of this, the second aim of this study was to characterize the differences between the trajectories of neuronal growth in (a) children, teenagers/young adults, and adults diagnosed with autism, and (b) age-matched control individuals.
Age-matched control individuals (healthy volunteers recruited from the local community by advertisement) who underwent an identical imaging protocol during the same period were also studied.
However, we found that the variability in DGCR6 expression was significantly greater in 22q11DS children than in age and gender-matched control individuals.
Healthy age-matched and sex-matched control individuals were recruited from the North West of England.
These were compared with 16 age- and sex-matched control individuals with sonographically intact rotator cuffs.
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