As would be expected, both CC and RC patients used significantly more healthcare resources than matched comparison patients (Table 2).
The study population, consisting of patients who experienced FN and matched comparison patients, was selected from the source population as follows.
The final study group included 1,193 cases and matched comparison patients (mean age: 49 years; 45% female; 54% white, 23% black, 23% other).
Using greedy matching techniques, we matched comparison patients 1 1 to treated patients on the linear predictor from the treatment model with calipers equal to 0.2 SD of the linear predictor distribution.
Among FN patients requiring inpatient care, the average number of FN events (irrespective of setting of care) was 1.10 (1.00-1.21 1.00-1.21.13 (0.08-0.18) for matched comparison patients, a difference of 0.98 (0.85-1.11).
Finally, since this analysis was conducted as part of a study that evaluated costs among older CRC patients and matched comparison patients[ 15], we also excluded patients who could not be matched to an appropriate comparator (less than 2% of the sample).
Figure 1 shows annualized trends in the excess number of office (a) and outpatient clinic (b) visits and inpatient stays (c) by cohort, treatment phase, and year of service (ie, trends in resource use among CRC patients relative to matched comparison patients).
Specifically, abusers spent an average of 6.2 more days in a drug rehabilitation facility and had, on average, 3.6 more days of hospitalization (+491 %), 1.7 more ED visits (+310 %) and 5.3 more outpatient/physician office visits (+137 %) annually, compared with matched comparison patients.
We enrolled 26 449 patients with GSDand 52 898 age-matched, gender-matched and comorbidities propensity-score matched comparison cohort patients with GSD who met the eligibility criteria for this study (table 1).
