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The intention was to achieve precise matching for patient characteristics in matched cohorts, as selection biases might confound comparisons between the treatment strategies.
The final sample sizes obtained for the matched cohorts were 681 and 948, respectively.
Three well matched cohorts were genotyped with seven common, potentially functional mtDNA single nucleotide polymorphisms (SNPs).
In the initial part of the study, we genotyped seven mtDNA polymorphisms in three well matched cohorts, in terms of both age and geography.
Accordingly, we used conditional Cox regression for matched cohorts.
Patient characteristics were similar across the matched cohorts (Table 2).
Similar(14)
In order to test this directly, we raised genetically identical, age-matched cohorts of y1w67c23 flies and subjected them to exercise-training at various ages.
Comparison between age-matched cohorts from 1980 to 2005.
The CSS was then compared in these PS-matched cohorts.
Additional file 2: Propensity-score-matched cohorts of patients alive at hospital discharge and 30 days.
All analyses were conducted in propensity score-matched cohorts of the study sample.
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