Sentence examples for matched clinical samples from inspiring English sources

Among these, ATOX1 is most outstanding since its expression was higher in tumor compared to normal tissues in 53% (out of 19 cases) of matched clinical samples analyzed.

The p21, PUMA and Bax biotin-tagged promoter sequences were generated (described in our Materials and Methods) and incubated with our lysed matched clinical samples, allowing the p53 protein to bind to these sequences.

Collectively, these observations are indicative of an inverse relationship between PAI-1 and miR-143/-145 in primary samples, which is further substantiated by a direct comparison of expression levels in matched clinical samples assayed by microarray and qRT PCR.

All of our matched clinical samples (tumour and normal tissue) were obtained during conventional surgical intervention and, importantly, none of our cancer patients had undergone any other form of disease management (chemo- or radio-therapy) prior to the surgical removal of the tumour mass.

To establish whether or not a direct connection exists between methylation profile detectable in tissues and cfDNA, we selected the same marker and an identical methodology in matched clinical samples, that is, PCDH10, which is one of the tumour-suppressor genes to be epigenetically silenced in CRC (Zhong et al, 2013).

PBMCs were obtained from the age- and gender-matched clinical samples including normal control individuals (HIV-1-/HCV) and individuals with HIV-1 mono-infection (HIV-1+/HCV), HCV mono-infection (HIV-1-/HCV+), and HIV-1/HCV co-infection (HIV-1+/HCV+).

Samples and matched clinical information were obtained from the Division of Urology at McClellan's Memorial Veteran's Hospital (Little Rock, AR, USA).

In the current study, surgical samples and matched clinical data were used to identify a prognostic marker, focusing on the genomic alterations of hepatic carcinogenesis.

We apply our model and identify 15 mutated loci in the PAXP1 gene in a matched clinical breast ductal carcinoma tumor sample; two of which are likely loss-of-heterozygosity events.

Our group has previously generated array-based methylome data on normal leukocytes and a number of colorectal tumors and matched normal clinical samples; therefore, we had other data to compare with the data generated by this approach.

To avoid this and to enable a safe and practical alternative, we recommend the use of magnesium sulphate anticoagulated blood samples for platelet counting if blood counts from EDTA samples do not match clinical expectations and/or are being flagged as suggestive of platelet aggregates by the automated haematology analyser.