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The total group of 43 BOSneg patients had lower Cav-1 serum levels than the healthy controls, but in contrast to the matched cases there was no difference in Cav-1 serum concentration between the 10 BOSpos patients and the total group of 43 BOSneg patients.
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There were no significant differences between the matched cases and controls after correcting for multiple testing with the Bonferroni procedure.
After removing 25 754 cases and 206 704 controls with <6 years of medical records or lacking a matched case or control, there were 88 125 cases of primary cancer matched with 362 254 controls, which were used in the analyses.
The study was nested within a cohort of 4,888 women with a histopathologic diagnosis of benign breast disease (BBD) and involved 61 cases and 71 controls, amongst whom there were 53 matched case-control sets.
Multicenter matched case analysis.
This represents the matched case.
This was a matched case-control study.
Matching by use of specific variables may not completely help eradicate bias as there may be other confounding factors not matched for and it is also possible to "over-match" cases and controls.
For 10 relatives, there was no matching case available for analysis.
Although in some cases the observed and predicted height:diameter ratios matched well, there were cases where discrepancies between observed and predicted height:diameter ratios would be unacceptable for practical management predictions.
However, if there are stable factors that improve the employment prospects for treated cases relative to matched comparison cases, earlier earnings would be higher for the WIA cases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com