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We then applied linear and logistic regression models corrected for matching in order to compare days from event to extubation, intensive care discharge, and hospital discharge in cases versus controls.[24] The day of event was defined as the day of VAC or VAP in cases, and the ventilator day on which the matched case patient developed VAC or VAP in controls.
Control subjects were selected at random from breast cancer patients born within 3 years and diagnosed with breast cancer within a year as their matched case patient.
Each control subject's at-risk period began with her date of breast cancer diagnosis and extended for the duration of her matched case patient's at-risk period.
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Plowman et al. (3, 4 ) assessed only patient-reported signs and symptoms of postdischarge SSI, and Perencevich et al. (5 ) relied on routine healthcare records for diagnosis/surveillance and matched case patients with controls on only 3 confounding variables.
Therefore, to include as many case-patients as possible in the analyses, we matched case-patients to controls by meal date.
Controls were questioned about exposures in the week before illness of their matched case-patient.
Controls were interviewed about the exposure period corresponding to their matched case-patient.
We interviewed controls about exposures during the same 3 days as the matched case-patient and made the same household observations.
Case-patients or their proxies were asked about exposures in the 7 days before illness onset, and control-respondents were asked about exposures during the same 7-day period as their matched case-patient.
Control subjects were eligible if they were in the same age-group as their matched case-patient (0 5 years, 6 17 years, 18 59 years, 60 years or older), had no gastrointestinal symptoms after 1 October 2001, and had not traveled abroad in the seven days prior to the onset of symptoms of the matched case.
Briefly, controls were randomly chosen from the list of patients who stayed on the same ward in the same calendar month as the matched case-patient and who were hospitalized for at least the same number of days by the day the culture yielded MDR A. baumannii in the study patient.
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