Sentence examples for matched benign prostate from inspiring English sources

Additional aims were to examine MIF expression, as well as the location of MIF's receptor, CD74, in human prostatic adenocarcinoma compared to matched benign prostate.

We used Enhanced Reduced Representation Bisulfite Sequencing, a genome-wide high-coverage single-base resolution DNA methylation method to profile seven localized PCa samples, seven matched benign prostate tissues, and six aggressive castration-resistant prostate cancer (CRPC) samples.

However, these data do not show any significant change in CD74 amount in tumor compared to matched benign prostate.

DNA was isolated from two different loci for each tumor in addition to matched benign tissue from frozen radical prostatectomy specimens of three prostate cancer patients.

As such, we present a triple-matched resource of prostate cancer copy number and expression profiling data, with matched benign tissue and blood, as well as a fully annotated TMA as an invaluable tool for further translational research into the mutational landscapes of primary and castrate-resistant prostate cancers.

There was no significant difference noted in staining intensity when comparing matched benign (mean intensity score = 0.6, Fig. 5C) and prostate cancer specimens (mean intensity score = 0.4).

The mean in situ hybridization intensity of prostate cancer was 1.5, significantly higher than in matched benign tissues whose mean score was 0.5 (Fig. 5A; p < 0.001).

We also identified putative tumour suppressor OLFM4 to have the highest fold-change in expression (all tumour versus matched benign), an effect recently ascribed to CN loss (19% in our data set) and linked to prostate cancer progression (Li et al., 2013).

In dataset 1 and 2, where the expression measurements of matched samples (prostate cancers and benign prostate samples from same patients) were provided, another method (Method b) was used to rule out the bias of single method.

MIF immunostaining was readily observed in both cancerous and benign prostate in the 21 matched samples (Fig. 4C and 4D).

RNA (miR and total RNA) was extracted from formalin-fixed, paraffin-embedded (FFPE) human PC (n=31) and matched adjacent non-cancerous normal prostate tissues or benign prostate hyperplasia tissues using a miRNeasy FFPE kit (Qiagen, Valencia, CA, USA) after laser capture micro-dissection based on pathologist reviews.