Alternative splicing isoforms are reported in such a way that at least one isoform (canonical or alternative) described in the entry matches a consensus CDS (http://www.ncbi.nlm.nih.gov/CCDS/).nih.gov/CCDS/
Although CHD4 does not display canonical PAR-binding domains (Karras et al, 2005; Ahel et al, 2008), sequence analyses revealed the presence of putative PAR-binding motifs in the CHD4 amino- and carboxyl-terminal regions that loosely matched a characterized consensus (Pleschke et al, 2000; Gagne et al, 2008).
Whereas in 1992 the king's words matched an emerging consensus that Suchinda had to go – and that Chamlong had gone too far – 18 years later there is no such common ground.
Previous studies with cloned IDE cDNA showed that the second ATG encoding amino acid 42, which better matches a Kozak consensus sequence, serves as the canonical start site for translation [9], [10].
The T20 region is conserved in Drosophila, C. elegans, and all mouse and human MEF2 homologs, and it matches a crude consensus site for AKT and p70 S6 kinase.
The transcript editing window shows the 2 bp in the intron immediately adjacent to each exon, and colours them green if they match a splice consensus, and red if they do not.
The observation of a de novo consensus that matches a "knowledge-based" consensus, both aligned along their entire lengths (+- 5%) indicates that this de novo consensus retrieved the exact and entire "knowledge-based" consensus.
By searching for novel motifs, we first noted that the flanks of the E CG) site often match an extended consensus MAACACGTGYG (M = A/C, Y = C/T).
To both give population size a degree of freedom and to match with a consensus estimate of human populations, we defined a gamma prior distribution with a mean of ∼10,000 individuals and a 95% confidence interval of 3,000 to 21,000 individuals [39], [40].
