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Exact(6)
From the fragmentation pattern of both CID and ETD spectra, the experimentalist can either read a partial or complete amino acid sequence or use automated search algorithms that match the fragment ions to a database of in silico fragmented peptides.
It appeared that the F.B.I. was just making sure that Mr. Kaczynski's DNA did not match the fragment it suspects belonged to the Tylenol killer.
Hence, the weight of each present fragment (i.e., the difference in predicted probability when the feature was swapped) is summed up for all atoms and bonds that match the fragment.
(^{(2)})Fragments with the lowest p value of a (chi ^2) test are removed; the test measures the correlation between the endpoint value distribution of all compounds, and the compounds that match the fragment.
A strategy to identify unknown compounds has consisted in the evaluation of a candidate by generating all its possible topological fragments in order to match the fragment mass with the measured peaks.
The second and third class of sequences (2.1, 2.2, and 2.5) were different from all other clones obtained in the study, unique to the second PCR amplification, and did not match the 3' fragment in the overlap.
Similar(54)
The binding mode modes of 8 presented in Figure 4 do not only match the fragment-based chemogenomics analysis reported in the current study, but are also supported by earlier reported site-directed mutagenesis studies, underlining the important role of E129, W183, Y153, and Y234 in ligand binding to 5-HT3AR, and the essential role of D3.32 and E5.46 in H4R-ligand interactions.
Moncin (David Dawson, a beacon of interest in the darkness, matched only by the forthcoming appearance of the brilliant Fiona Shaw as his domineering mother) says he did own a suit that matches the fragment we have had exhaustively explained to us but he donated it to a tramp a week ago.
For instance, the subjects could have learned whole objects during training and, during the subsequent testing, could have performed the categorization task by simply matching the fragment to the most similar whole object.
Matching the fragment somewhere else in the contact graph may result in a consistent matching, or may produce another conflict, potentially fixed by replacing part of the conflicting fragment with the new fragment.
In the second fragment three classes of sequence were obtained, represented by clones 2.3 and 2.4; these were identical to the clones from the first PCR and matched the 3' fragment in the overlap.
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