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Overall, when comparing standard PET/CT and basic PET/MRI with body coil acquisition the basic sequence needed for the MRAC PET/MRI does not entirely match the diagnostic accuracy of standard low-dose PET/CT.
In addition, doctors must pay attention to those who do not perfectly match the diagnostic criteria.
Our initial results suggest that the use of mosaics allows semi-automated ROP analysis programs such as ROPTool to better match the diagnostic assessments of human experts.
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The SPE group comprised women matching the diagnostic criteria of the ISSHP: two blood pressure readings of ≥160/110 mmHg were taken at least with >5 g proteinuria over 24 hours or +3 on dipstick analysis.
The MPE group comprised women matching the diagnostic criteria of the International Society for the Study of Hypertension in Pregnancy (ISSHP) [ 29]: two blood pressure readings of ≥140/90 mmHg were taken at least with >300 mg proteinuria over 24 hours or +1 on dipstick analysis.
Between 2004 and 2012 176 patients with suspected PPCM were reported to the German PPCM registry of whom a total of 115 patients matched the diagnostic criteria defined by Sliwa et al. [ 24] while 61 patients did not meet the diagnostic criteria, i.e., EF ≤ 45%% and absence of previously known cardiomyopathy.
Overall, PET/MRI with body coil acquisition does not match entirely the diagnostic accuracy of standard low-dose PET/CT.
PET/MRI with body coil does not match entirely the diagnostic accuracy of standard low-dose PET/CT.
Mainardi et al. [22], however, proposed that patient's symptoms do not match with the diagnostic criteria for AH and hence it is unclear whether vasoconstriction in the cerebral arteries can be a cause or a consequence of AH.
Overall, PET/MRI with just one sequence using a body coil does not match entirely the diagnostic accuracy of standard low-dose PET/CT and thus, might only serve as a back-up solution in very limited cases.
Finally, the authors might include a more refined phenotyping of HAND and in particular one that matches the current diagnostic criteria in any future development of the database [ 6].
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Justyna Jupowicz-Kozak
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