In addition, our algorithm DPC outperforms the previous algorithms CMC, SPICi, MCL, and HC-PIN on the number of perfect matches, specificity and sensitivity and F-score.
Specificity was close to 100% for all cases, meaning that not a single pair was misclassified as a false-positive, but when we considered records with patients' names only, even for exact matches specificity was unacceptably low (approximately 82%).
Furthermore, T2-A3 cells pulsed with gp100614-622 or tyrosinase325-334 were specifically killed by T cells with matching specificities (Supplementary Figure 5a and b, respectively).
Antibodies targeting well known glycan epitopes and the membrane proximal region of gp41 were detected in genital secretions, and matched specificities in plasma.Women with plasma bNAbs have overlapping specificities in their genital secretions, indicating that these predominantly IgG isotype antibodies may transudate from blood to the genital tract.
We incubated HAEC with sera containing HLA-Ab of matching specificities (see Table S1).
Initially, 39 self-report items were developed in order to match the specificity of aggressive behavior among children that commonly takes place in the school context.
Cycling conditions were defined to match primer specificity and limit nonspecific amplification by using the touchdown approach, which features progressive reduction of annealing temperature during cycles.
Accessible peptides that match the specificity of these motif-binding domains are continuously created and destroyed by mutations in rapidly evolving disordered regions, creating a dynamic supply of new interactions that may have advantageous phenotypic novelty.
Since they typically identify secondary host reactions, surrogate biomarkers of prion infection cannot aspire at matching the specificity of PrPSc detection.
Keeping only the conserved sites from the set of seed matches lifts specificity of all seed types (Fig. 2, Supplementary Table S9).
