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All prostate cancer probe data sets were filtered to remove all probes whose perfect match signal was not greater than its mutant signal.
Affymetrix Canine_2 microarray chip data were normalized and filtered; we used robust multiarray average (RMA) to obtain mean values for the intensity of the probe pairs and define the expression levels of the mRNA based on modeling perfect match signal intensities and ignoring mismatch signal [46].
RMA starts with a non-linear background correction based on a single chip to detect the perfect match signal.
Gene expres-sion measures were computed based on a non-linear multi-chip model of the perfect match signal [ 66].
As long term memories become updated with this information, expectations for a reward will decline, and this will result in an eventual "match" signal by hippocampus.
Consistent with previous findings [ 10], the effect of a one-base mismatch was found to be variable, reducing the hybridization signal to 39% or 47% of that of the corresponding perfect match signal.
Similar(53)
This match signalled United's coming of age in Europe.
That match signalled the end of Graeme Smith's extraordinary reign as South Africa captain and leaves the team with two significant holes to fill in the future.
But Schalk Burger, who had missed the first match, signaled his return in typical fashion, shoving his hand into Luke Fitzgerald's face, groping for a few seconds and then gently, almost affectionately, shoving his fingers into the Irishman's eyes.
This approach is based on our new one-dimensional (1D) spline-based genetic algorithm to match signals.
As more context match signals are generated by hippocampus, prefrontal cortex may down-regulate the excitatory drive that it was imposing on striatum when the mismatch signals first occurred (Fig. 7D4).
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