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Birth certificate matches were made for 916 cases, resulting in a match proportion of 83%.
A final algorithm that used multiple combinations of identifying variables resulted in a match proportion of 87%.
There were 186 AML cases eligible to be in the study, of whom 154 matched to birth records, resulting in an estimated match proportion of 83%.
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Regarding the second limitation, with a successful matching proportion of 89%, this means that about 11% (N=241) of the enrolled children were erroneously classified as non-enrolled.
They were compared with ANCA-negative IgAN patients (n = 40) and ANCA-associated systemic vasculitis (AASV) patients (n = 40) with a randomly selected and matched proportion of crescentic glomeruli.
Forty ANCA-negative patients with IgAN and 40 AASV patients were selected by stratified random sampling as two control groups, with matching proportions of crescentic glomeruli.
Tables 1 and 2 and Figure 1 show the comparison of clinical and histological data, response to therapy and prognosis among ANCA-positive IgAN, ANCA-negative IgAN and AASV patients with matched proportions of crescentic glomeruli.
With matched proportions of glomeruli with crescents, ANCA-positive IgAN patients showed worse renal function at renal biopsy, but tended to have a better response to aggressive immunosuppressive therapy in the short-term and a greater possibility of withdrawal from dialysis, when compared with ANCA-negative patients, and were similar to patients with AASV.
Regarding the matched proportions of crescentic glomeruli, ANCA-positive IgAN patients showed a trend of lower eGFR compared with ANCA-negative IgAN patients, but were consistent with AASV patients at baseline [21.2 (10.9, 47.7) mL/min/1.73 m versus 47.0 (87.1 87.1) mL/min/1.73 m versus 19.5 (9.2, 52.4) mL/min/1.73 m, P = 0.12].
Local governments would match a proportion of the contributions and place most of the money in state banks.
We also did not match the proportion of smokers when recruiting non-arthritis controls and this could influence the severity of periodontitis.
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