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Analyses of Phase I data indicate reproducible levels of compound behavior that match previously known toxicological responses (Huang et al. 2008).
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Indeed, under-represented motifs found solely on a statistical basis matched previously known leaky scanning signals and were also confirmed independently [ 36].
These findings made it possible to further divide the DRG neurons into six distinct subsets that matched previously known groups of somatosensory neurons, and also identified new ones.
In order to computationally identify miRNAs in sugarcane, we developed a homology-based strategy based on [ 7, 13] that included the following steps: First, we searched the sugarcane EST and GSS databases to find sequences matching previously known plant miRNAs.
In previous studies performed with massive sequencing techniques a similar or even higher number of unigenes did not match with previously known sequences representing newly detected transcripts [ 44, 49, 55, 57].
A total of 3631 novel miRNA candidates were identified in potato that met our criteria and had no matches to any previously known plant miRNAs.
When 181 patients admitted with acute MI and no history of diabetes mellitus were compared to 180 matched controls without previously known diabetes or cardiovascular disease, glucose, HbA1c, proinsulin, proinsulin/insulin ratio, triglycerides, insulin resistance and fibrinogen were all consistently higher in patients than controls (P < 0.01).
The significantly high proportion of new microRNAs matching seed sequences from previously known microRNAs suggests the presence of new family members, perhaps by a seed-conservative evolutionary mechanism.
What size woods do you use?' Alan Horwell, the club's match secretary, explained that Kings was previously known as the Princess Bowling Club and went into detail about the arduous nature of procuring and maintaining a green comprising the best surf-sprayed Cumberland turf.
In total 8,363 transcripts of C. lectularius were assigned for Gene Ontology (GO) terms based on BLAST matches with sequences whose function is previously known (Figure 4, Table S1).
The matches will be aired on the British ESPN channel, previously known as ESPN America, it was announced yesterday.
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