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Perfect seed matches to all currently annotated human miRNAs were identified in each of the Compugen sequences using either an in-house Perl script which counted seed match occurrence and recorded the position of each within individual 201 nt Compugen sequences (as illustrated in Fig. 1), or an in-house Excel-based analysis, and using the standalone version of Targetscan (Targetscan 5.0).
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We use MotifScanner from the inclusive package by Thijs et al. (2002) to scan sequences for the best matching occurrence of a PWM; in case of an oligomer, we use a regular expression pattern with decreasing discriminative power to find the closest match.
The matching occurrences are sorted after extracting them from the suffix tree to obtain the pos-list in sorted order.
MedEvi further identifies additional keywords of biological and statistical significance from local context of matching occurrences in order to help users reformulate their queries for better results.
We believe that a concordancer is a good candidate to meet the above-mentioned tasks of information seeking, since it innately deals with the local context of matching occurrences where the evidence being searched is much more likely found than in other parts of the retrieved documents.
Motif 02 (CLxxxxLHM) produced the best fidelity match and occurrence hits (Additional file 9: Table S3).
Their own joint act of faith had brought them here at the very moment and matched its occurrence, and proceeded as it proceeded.
Tuning the threshold could have, for instance, the aim to achieve a number of positive predictions that matches the occurrence of positive human samples in the training data.
The matches (any occurrence of similarity between a P. edulis BES and a specific region used for comparing genomes) were classified into six categories based on the classification in Rampant and co-authors [ 27].
To do so, a Levenshtein distance-based word identifier computes the Levenshtein distance between the phone sequence given by the phone-based recognizer and the phone transcription of the OOV term so that a low Levenshtein distance match suggests the occurrence of this OOV term.
In addition, we looked for solar flare occurrences that match the time of each Esb occurrence using measurements of X-ray radiation in the range 0.5 4.0 and 1.0 8.0 Å.
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CEO of Professional Science Editing for Scientists @ prosciediting.com