Your English writing platform
Discover LudwigSuggestions(1)
Exact(2)
Another challenge involved developing a novel computational method for reconstructing a "master sequence" for clinical patient samples with unknown sequences from the resulting reads obtained from the Illumina sequencing.
A compotype's center-of-mass is found to be analogous to a master sequence for a sequential quasispecies.
Similar(58)
Since we don't have experimental data of quasispecies profiles with such detail, it is difficult to determine a critical value for f C, f C * However, the scant experimental data seem to favor small values of -the average % of viral variants whose population represent at least 1/2 of the master sequence-for different f C and normalized Shannon entropy S n is shown.
Altogether, we conclude that stallers are an intrinsic problem for the system, and that the master sequence of the full model has evolved some "mutational control" over them.
In other words, the master sequence codes for the information of the entire ecosystem, whereas the decoding happens, stochastically, through mutations.
We conclude that in the full system helpers are only favorable for the master sequence (and, possibly, for the units of replication very close to it), because of its lack of parasites in both the mutational and the physical neighborhoods.
Use each representative PDB sequence both as a master sequence to generate a subgroup profile alignment and as the "consensus" sequence for that subgroup.
More specifically, we iteratively applied the following seven-step procedure: Use each representative PDB sequence both as a master sequence to generate a subgroup profile alignment and as the "consensus" sequence for that subgroup.
Briefly, the site mapping algorithm counts the gaps in the homology string sequence for each RPS-BLAST hit to map the curated sites in the CDD master sequence onto the implicit PDB sequence.
However, the usual mathematical criterion for defining the error threshold is the loss of master sequence in the absence of back mutation.
Helpers make up to about 50% of the mutational neighborhood of the master sequence, in contrast to the case of random sequences (≈ 10%% ) and those optimized for replication.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com