Your English writing platform
Discover LudwigSuggestions(1)
Exact(2)
The master sequence does not seem to differ much from random sequences for what regards junk, stallers, and hybrids.
This fact, together with very low single nucleotide errors for humans, implies that the fitness of mutants of an hypothetical master sequence does not change significantly, and the fitness distribution of mutants around the master sequence is likely to decay linearly, or sub-linearly, a scenario under which no error threshold is possible.
Similar(58)
In other cases, however, MITEs share their terminal sequences with canonical elements, but their internal sequence does not have similarity to the master copy.
Moreover, when genotype and phenotype are decoupled in models of evolution, it turns out that the most abundant sequence does not necessarily coincide with the master sequence, i.e. the fittest sequence, as defined in quasispecies theory.
The sequence does not matter.
The resulting network revealed that Tnt1, Retrolyc1 and Retrosol did not share any RNAseH sequence as revealed by the absence of shared nodes, although different species within each genus did share a master sequence.
Although units of replication are increasingly neutral at higher Hamming Distances, they do not outcompete the master sequence.
However, the cases that resist to the highest mutation rates do have a unique master sequence (1., 2., and 3. in table 1).
The sequencing revealed only one master sequence with a few point mutations (Supplementary Figure S1C).
First, the master sequence, i.e. the sequence with the highest replicative ability, is lost [ 1].
Most of these recurrent mutations belonged within the master sequences.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com