Sentence examples for master role in from inspiring English sources

This hypothalamic nucleus also contains neuropeptide Y (NPY) neurons which play a master role in the effect of ghrelin on feeding.

Circadian rhythm genes have recently been related to replication, damage responses and carcinogenesis and may play a master role in cell division[43].

IL-23, a member of the IL-12 cytokine family, has a master role in regulating TH-17 development [8], [9], [18].

Snail1 appears to have a master role in EMT, although several other factors such as Snail2 (Slug), Zeb1 (δEF1), Zeb2 (Sip1), Twist1, E47 and E2-2 alsoalso known to induce or contribute to the EMT in different types of cells [2], [3].

p53 has attracted tremendous attention due to its master role in tumor development.

In contrast, in tomato plants a single HSF, LpHSFA1, appears to play a master role in vegetative thermotolerance [ 29].

TFs have been demonstrated to play master roles in response to various abiotic stresses via modulating target gene expression [ 38, 39].

Although the in vitro evidence indicated a master role of Wnt5a in inducing aggressive tumor phenotypes, the prognostic impact of Wnt5a expression in pancreatic cancer appears not to be of significance.

Many studies have suggested master role of habenula in control of adaptive behavior through regulation of brainstem aminergic nuclei.

This would be consistent with a master role for caspases in the downregulation of BCL2 and MCL1 after bortezomib treatment.

In conclusion, a master role for GADD45A, and CDKN1A (P21) in the general response to irradiation is confirmed but other interesting candidates have been identified whose role could be clarified in various cellular systems in the future.