Sentence examples for master regulator to from inspiring English sources

Altogether, our findings suggest that OsSND2 may function as a master regulator to mediate SCWs biosynthesis.

Furthermore, molecular characterization of OsSND2 suggested that it functions as a master regulator to directly mediate the expression of other MYBs and facilitate cellulose biosynthesis.

Studies suggested that the transcription factor Rest acts as a master regulator to suppress premature differentiation of neuronal progenitors and secure orderly neuronal maturation.

Through gain- and loss-of-function assays, we show that the foxi3a-foxi3b regulatory loop functions as a master regulator to mediate a dual role of specifying epidermal ionocyte progenitors as well as of subsequently promoting differentiation of Na+,K+-ATPase-rich cells and H+-ATPase-rich cells in a concentration-dependent manner.

We reasoned that the upstream regulators or transcription factors (TFs) of these prognostic signatures might take a critical role as driver or master regulator to provide clues on the underlying regulatory mechanisms and therapeutic applications.

This observation is consistent with the idea of regulatory gene cascades, that genes involved in regulation are themselves tightly regulated, allowing master regulators to exert overall control of gene regulation 'programs' to reprogram cells [ 28].

This strategy could also be applied to TFs associated with the signalling pathways controlled by master regulators to up-regulate the expression of certain genes.

The crux of his idea was to add genes called master regulators to the skin cells' chromosomes.

Because of their ability to simultaneously control the expression of a large number of genes, miRNAs are well-positioned as master regulators to maintain or switch cell fate.

Finally, we discuss the relevance of these master regulators to engineering of crops to meet the needs of the changing world.

Targeted expression is particularly needed for genes, such as those that are master regulators, to diminish or better control pleiotropic effects.