Sentence examples for master regulator is from inspiring English sources

This result is in agreement with the E. coli transcription profile of the stringent response, where the expression of the flhDC flagella master regulator is rapidly down-regulated [ 70].

The CtrA cell cycle master regulator is a critical element of the core machinery that regulates cell cycle progression.

Thus, calling BZR a master regulator is not fully justified.

Foxp3, as a master regulator, is important for the development and function of Tregs [ 34].

The p16/pRb pathway, another senescence master regulator, is also commonly affected by novel senescence-associated molecules [ 28, 32].

For some cell types, a master regulator is present at many of the enhancers, such as TAL1 in erythroid cells, and ChIP-seq data for that regulator will greatly improve the specificity of enhancer predictions.

The SOS network is a highly conserved system [ 8, 24] and consists of about 30 genes, the master regulator being gene lexA.

Taking advantage of the global molecular network developed from information contained in Ingenuity's Knowledge Base, known targets of the master regulator were included in the network, whereas the non-differentially expressed molecules were excluded.

The paramount importance of the master regulators is that they can control most of the difference in gene regulation patterns that are observed in the disease phenotypes through their extensive regulatory connections.

Modification of the activity of master regulators is a promising strategy for plant stress improvement that should increase the plasticity of the plant responses and adaptation as many genes and enzymes are under their control.

Notably, in the constructed network all master regulators were significantly up-regulated and included PDIA4, APEH, PEBP1 and APOE while the protein expression of ARG1, FBP1 and HAAO was repressed (see Additional file 13: Figure S2A-G).