Sentence examples for master regulator for from inspiring English sources
Among intracellular metabolites, α-keto acid such as αKG turns to be a master regulator for catabolite regulation and co-ordination of different regulations [139].
Scleraxis may thus be a master regulator for tenocytes, and regulation of fibrillar collagen synthesis may represent one aspect of this role.
This was confirmed at the genomic level by strong up-regulation of Hif1a, which acts as the master regulator for the expression of genes involved in the hypoxia response in most mammalian cells [ 42, 43].
This miRNA would appear to be a master regulator for several aspects of immunity, including the regulation of cytokines, such as tumor necrosis factor-alpha (TNF-α), functioning in the negative feedback control of innate immunity in Toll-like receptor (TLR) signaling, and is involved with T-cell activation and is highly expressed in mature human memory T cells [ 41].
They act as master regulator for developmental genes, which involves coordinated actions of various auto and cross-regulatory mechanisms.
The promise of inhibition of such a master regulator for cancer therapy is the potential to cause combinatorial inhibition of multiple oncogenic signaling pathways simultaneously.
Recent studies of tomato HSFA1a mutants and an Arabidopsis HSFA1a/1b/1d/1e quadruple mutant revealed that members of HSFA1 genes can function as master regulators for the HSR and play important roles in cross-regulation for abiotic stress responses (Mishra et al. 2002; Liu et al. 2011).
Nevertheless, significant progress has been made in the identification of signaling pathways and master regulators for drought tolerance.
This has been followed up by a number of additional manuscripts published or in review where this approach has elucidated master regulators for a variety of cellular phenotypes.
Once the master regulators for all of the tumors in the database have been identified, tumor samples in the top 20 cancer types represented in TCGA will be reclassified, using a pan-cancer approach.
A regulatory protein blocks the expression of non-neuronal genes in nerve cells, find Bio-X affiliates Marius Wernig, Thomas Südhof, and Lars Steinmetz, and Travel Awardee Cheen Euong Ang, suggesting there are many master regulators for cell types.
