Sentence examples for master loci that from inspiring English sources

The authors studied master loci that control transposable element proliferation in Drosophila but were molecularly uncharacterized for many years because of the apparent lack of functional sequences at the loci, other than a jumble of transposable element insertions.

This complex, in turn, cleaves the antisense transcripts that originate from master loci such as the 20A locus.

These master loci were found to produce piRNAs that repress transposable elements in trans [ 22].

Our data suggest that Cuff regulates the piRNA master loci presumably acting in a complex with the HP1 variant Rhi.

Our current data strongly suggest that stem- and germ-cell loss in the cuff mutant is caused by a failure to express the piRNA master loci.

Thereby, we propose that the truncated copies of HeT-A retrotransposon at the telomeres could act in a similar way than truncated copies from master loci such as flamenco, acting to control transposition of other Drosophila retrotransposons (gypsy, Zam and Ideafix) [ 24, 25].

We created hPSC master cell lines suitable for FLPe recombinase-mediated cassette exchange (RMCE) in the AAVS1 locus that allow generation of transgenic lines within 15 days with 100% efficiency and without random integrations.

In addition there is a central, master regulator of virulence, the Agr system, which is encoded by a four-gene locus that regulates pathogenesis, and the shift from localized to invasive phenotypes [19] [21].

Here is the locus that recently contained this tree spirit.

Focusing in particular on a large heterochromatic-like domain that flanks the Xist master locus, this study has revealed new functions for the Tsix antisense transcript in controlling levels and distribution of H3K27me3 together with gene expression over an extended sub-region of the Xic.

The ping-pong model proposes that small antisense piRNAs associated with AUBERGINE or PIWI interact with sense RNAs produced by target TEs copies and cleave it, in order to induce the production of small sense piRNAs associated with AGO3, which in turn will interact with antisense transcripts produced by the master locus of repression.