Sentence examples for master genes and from inspiring English sources

Today they are making stunning progress in discovering the master genes and proteins that regulate how we age.

In addition, we used long-RNA transfection to search for early targets of reprogramming factors in fibroblasts, and we provide evidence that the pluripotent-stem-cell master genes and reprogramming factors Sox2 and Nanog are novel upstream effectors of the proto-oncogene Hmga2.

However, the identification of master genes and key biological processes involved in the initiation of liver compensatory growth after removing the ventral lobe remains a challenging task.

To analyze the phylogenetic relationships of master genes and pseudogenes, we compared all intron 30 sequences by carrying out a CLUSTALW alignment.

It is generally accepted that most, if not all, large mammalian families of TEs originate from a small number of actively expressed copies called "source", "founder" or "master" genes and produce discrete families of "repetitive elements".

To identify master genes and molecular mechanisms implicated in luminal B biology, we used a strategy based on an integrated profiling study that combined high-resolution analysis of genome copy number aberrations (CNA) by array-comparative genomic hybridization (aCGH) and gene expression in luminal A and luminal B primary tumours.

Surprisingly, in the chimpanzee, a gene conversion between the PKD1 master gene and pseudogene 2 is indicated (Additional file 3).

The identity of the SD master gene, and how it interacts with the minor genetic and environmental factors, however, remains elusive.

At the cellular level, it was shown that bone marrow MSC culture, when exposed to strontium (Sr), displayed a significant increase in the expression of the master gene and Runx2, as well as bone sialoprotein (BSP), and this was associated with a significant increase in the formation of colony-forming unit osteoblasts (CFU-obs).

To better understand the mechanism of flowering of japonica rice, cultivated in Northern latitudes adapted to LD conditions, in this study we analyzed the allele distribution and the expression of the master genes, RFT1 and Hd3a, and their immediately regulators, Hd1, Ehd1 and DTH2.

Conversely, p53 downregulation leads to a strong inhibition of the mesodermal master genes Brachyury and Mesp1 affecting cardiomyogenesis and skeletal myogenesis of ESCs.