Sentence examples for master gene in from inspiring English sources

In 1990, Bernard Roizman, a virologist at the University of Chicago, found a "master gene" in the herpes virus.

Runx2 is known to be an important regulator of cell phenotype commitment and growth [22] [26] and is considered a master gene in bone as it is essential for osteoblast lineage commitment, differentiation, bone matrix formation and mineralization [27] [29].

A complete backwards gene conversion event appears to have inactivated the AluYh3a3 master gene in humans.

In particular, Pax6 is a master gene in eye development in both vertebrates and Drosophila.

In the case of AluYh3a3, such an event has resulted in inactivation of the putative master gene in humans.

Moreover, there are six pseudogenes of PKD1 that are located proximal to the master gene in 16p13.1.

Gene optimization has been used to improve expression of the antibody master genes in the library context.

MSX1 protein is a classical transcription regulator which promotes cell proliferation and inhibits cell differentiation by inhibiting master genes in tissues such as bone and muscle.

This scenario resembles the recently described unusual 'bivalent' chromatin structure occurring at promoters of master genes in ES cells, where both active and repressive chromatin marks are physically present at the same nucleosomes [53], [57], [58].

This approach is very promising for understanding gene-gene correlations and finding master genes in target conditions.

Figure 4 shows the different expression of some known tumor master genes in SH-SY5Y cells in comparison to the differentiated cells.