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Recent studies have confirmed that PTHrP massively contributes to malignant behaviour of oral cancers-cell proliferation, migration and invasiveness.
It massively contributes to our common well-being -- whether or not you choose to listen to it, you benefit by living in a more informed society -- and a more prosperous country.
Several studies have demonstrated that this shift massively contributes to satisfying the high bioenergetic and biosynthetic demands for rapid cell division in cancers [ 12– 12].
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He told The Independent: "Ukip has served its natural purpose…Nigel [Farage] massively contributed to securing the referendum".
No one courted the Murdoch press with more enthusiasm than Mr Blair, massively contributing to their influence and power in British politics.
By funding privatisations, land grabs and dams, by backing companies and governments accused of rape, murder and torture, and by putting $50bn into projects graded highest risk for "irreversible and unprecedented" social impacts, the World Bank has massively contributed to the flow of impoverished people across the globe.
Today, the inconsistency between moral claims of adhering to human rights and democratic values by the west, while continuing to support authoritarian leaders who are oppressing their own people, is massively contributing to anti-western sentiment in Iraq and the Middle East at large – a sentiment that is unfortunately expressing itself through violence.
We therefore conclude that Dbx1-derived cells do not massively contribute to some of the territories that are most affected in ablated mutants, namely the forebrain and face, suggesting that the defects observed are non cell-autonomous.
Although the inhibition of apoptosis by itself is normally not sufficient to cause tumours, experimental prevention of apoptosis in mice could massively contribute to tumour development when proliferation was concomitantly enhanced (Vaux et al, 1988; Strasser et al, 1990).
Knowledge about specific marker molecules, which could distinguish between fibroblasts from different anatomic sites, as well as between fibroblasts at different functional or disease-related states, would massively contribute to the understanding of patho-physiological mechanisms.
This hypothesis was confirmed when Iwano showed that tubular epithelial cells bearing the reporter gene lacZ massively contributed to the pool of interstitial fibroblasts (up to 36% of all fibroblasts) in a model of mouse renal fibrosis induced by unilateral ureteral obstruction [ 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com