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Many of these drugs appear to have low toxicity profiles, so biological responses are expected below drug concentrations, which lead to massive side effects.
Although it is possible that an antibody actively crosses the blood-brain barrier, the concentrations efficient for tumors are likely lower than those required to reach the brain parenchyma and to cause massive side effects [ 295].
If they only tested it on elephants, then its one massive side-effect, that it turned you into an elephant, could easily have been missed.
As a result of this, a large increase in tumor drug concentrations (tenfold or higher) could be achieved relative to administration of the same dose of free drug, (Maeda et al. 2000) thereby decreasing the massive systemic side effects of conventional chemotherapy.
Furthermore, their presence in GM corn means that truly massive unexpected side effects have taken place in the plants' biochemistry.
Her violent upset loss to Holm temporarily derailed that gravy train, but it did have one notable positive side effect: a massive rematch that could set records as the biggest fight in the history of the sport.
That is a side effect.
Yes, like a side effect.
A side effect?
But they tended to be on the massive side".
Side Effect.
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