Sentence examples for massive sequencing technology from inspiring English sources

In recent years, development of massive sequencing technology has led to new possibilities for high-throughput genome analysis [ 3].

The massive sequencing technology generates enormous amounts of candidate genes potentially involved in pheromone biosynthesis but testing their function by heterologous expression or gene silencing is a bottleneck.

Sequences derived from the OLEA EST database [ 35], a collection of over 102,000 Olea europaea L. fruit EST reads generated through 454 massive sequencing technology [ 30], were analysed to identify transcripts putatively involved in the pathways of terpenoids, phenolics and other secondary metabolite synthesis.

In addition, in the last few years massive sequencing technologies have also been developed for transcriptome analysis [ 7, 24, 35].

In this review, we focus on the disease-specific gene mutations in MLN discovered by recent massive sequencing technologies.

The main weaknesses of sequencing strategies are library bias, cost, availability, and difficulties in data management and analysis, although the cost of massive sequencing technologies is rapidly decreasing.

Available massive sequencing technologies, leading to the simultaneous analysis of hundreds of different genetic regions, are increasing the molecular characterization of solid tumors.

The errors that occur in SNVs discovery when using massive sequencing technologies have several major causes: (1) PCR artifacts, (2) sequencing errors, and (3) errors in the mapping of short reads to the reference sequence.

Today, given the constant improvement in cost/benefit of massive sequencing technologies, it is possible to think in whole genome shotgun (WGS) approaches to try to answer global internal group diversity.

Before massive sequencing technologies became available, phenotype-related ENU-induced mutations were short-listed in a lengthy procedure of out-crossing and meiotic mapping that identified linkage chromosomes, or finer linkage regions of approximately 20 MB.

The increasing availability of genome sequences through the application of next-generation massive sequencing technologies has allowed the study of genomic polymorphisms at both the interspecific and intraspecific levels, thus helping to understand how species adapt to changing environments through genome variability.