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Capture and massive sequencing of exons of candidate genes obtained using SureSelect Human All Exon 51 Mb kit (Agilent) and Hiseq2000 (Illumina) 30x tests.
The integration of the functional analyses provided by the massive sequencing of bacterial genomes and metagenomes will allow the rational production of a desired prebiotic molecule with specific functional properties.
To further their study, the scientists have called for "massive sequencing" of human DNA, particularly from African patients who have been exposed to HIV the longest.
For that reason, DNA barcoding approaches and the massive sequencing of multiple markers are obviously not mutually exclusive.
Large international consortia are currently pursuing massive sequencing of cancer genomes and comprehensive characterization of the human epigenome.
The massive sequencing of several cancer genomes has led to the identification of thousands of mutated genes.
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More formally, a data stream (mathcal {S}) is a massive sequence of examples ({mathbf{x}}_1, {mathbf{x}}_2, ldots, {mathbf{x}}_N), i.e., (mathcal {S} = { {mathbf{x}}_i }_{i=1}^{N}), which is potentially unbounded ((N rightarrow infty)).
However, despite of massive sequencing, loss of rare transcripts is possible.
Actually, hundreds of thousands of DNA variants are detected in massive sequencing projects of genetic disorders.
Thirty-five olive transcripts homologous to genes involved in the pathways of the main secondary metabolites were identified from the massive sequencing data of the olive fruit transcriptome or from cDNA-AFLP analysis.
The ability to detect these multiple events may result from the massive sequencing capability of the Illumina/Solexa platform, compared with previous high throughput methods.
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