Sentence examples for massive rewiring of from inspiring English sources

These results indicate that the two diseased-states of multiple sclerosis, the relapse and the remission, have a strong effect on the coexpression relations between the selected ncRNAs and mRNAs and produce a massive rewiring of the ncRNA – mRNA network.

Our results suggest that the diseased state of RRMS has a strong impact on the ncRNA – mRNA network of peripheral blood leukocytes, as a massive rewiring of the network happens between conditions.

A recent study has shown that the addition of a DNA damaging agent (methyl-methane-sulfonate (MMS)) produces a massive rewiring of the genetic functional interaction network in yeast [ 38].

This obviously does not exclude local changes and possibly also transposition events after the mouse/human divergence, but suggests that these should not be the rule and that a massive rewiring of this subnetwork in the last 100 Myrs should be excluded.

The authors created genetic networks based on functional interactions between the 418 genes of yeast for both the untreated and the MMS-treated conditions and observed that from the 3126 unique interactions present in any of the two networks, 2050 (65.56%) were condition-specific, demonstrating that the sole addition of a DNA-damaging chemical agent produces a massive rewiring of the network.

Based on that, it seems that a massive rewiring of the ncRNA – mRNA correlation network happens between conditions, which, although has little impact in topological features, provokes a big change in which ncRNAs play a central role in each of the networks (Table  1).

Taken together, our data indicate that a highly common pool of genes is modulated by the two modulators while massive rewiring among these genes exists across different conditions (i.e., ESR1 or ERBB2 alone, and co-modulation).

As for the genetic functional interaction network created in yeast, some evidence suggests that coexpression networks also undergo massive rewiring between different conditions.

Behind the collapse was the rewiring of Wall Street.

This helps avoiding rewiring of simulation models on each engagement.

With less panache, Andrew Lansley unveiled a complete blueprint for a rewiring of the NHS with such haste that it soon had to be rewired itself.