"As president, I will immediately stop this massive regulation.
As with any new and massive regulation, the implementation was bound to be difficult in the beginning.
Ian Gregory, of campaign group Vapers for Britain, said: "In its assessment, the Department of Health has not been able to quantify any benefit from the massive regulation of e-cigarettes".
It could be a minor version of the way FDR's incessant experiments in the 1930s price and wage controls, massive regulation, huge tax increases, forced unionization severely damaged the U.S.' climb out of the Great Depression.
Taken together, these data suggest that numerous activating factors are highly enriched at group I promoters, indicating a massive regulation, which consequently leads to higher transcriptional activity ('hyperactive') (Fig. 5c and d; Additional file 1: Figure S3e and f).
Since miRNAs are key regulators of cellular proliferation and differentiation, we hypothesize that the weaning phase is accompanied by massive regulation of specific miRNAs governing the reorganization of the intestinal cellular response.
Massive government regulations my nose!
Dom then continued: "Then there were massive government regulations, three wars, financial crises and the struggles with new technology (at one time comprised of cable, satellite and VCRs).
Therefore, for these gene transcripts to produce equal amounts of protein, as suggested in Skene et al., massive up-regulation of protein translation is required from MECP2 transcripts or massive down-regulation of protein translation is needed from Histone transcripts.
Whereas cell-wall metabolism enzymes (the autolysin lytM, and several amidases lytA, sgtA and SA1759) showed drastic up-regulation, transpeptidase, acid techoic synthesis genes, the mur operon and several cap genes showed massive down-regulation after internalization (additional file 3).
