My excitement about the future for i is obviously mixed with sadness about The Indy eventually stopping in print – although its future in digital is, with the massive new recruitment underway, dazzlingly bright.
We show that ets-1 promotes massive cell recruitment and induces local degradations of the basal lamina, two separable events which are sufficient to initiate ectopic delaminations.
The best model for testing the pathogenic hypothesis on Baló's sclerosis would be the experimental allergic encephalomyelitis of the common marmoset, where concentric lesions with high oligodendrocyte depletion and massive macrophage recruitment are reported [21].
Infection of immunodeficient B6.RAG-2γc−/− mice with a low dose (102 PFU) of HKx31also induced massive neutrophil recruitment to the airways (Fig. 6A) yet neutrophil depletion during the later stages of infection (i.e. from day 5 onwards) did not ameliorate disease (Fig. 6B).
Parasites use mechanisms like inhibition of antigen presentation to escape immune response, however, a high growth rate induces massive macrophage recruitment [ 13].
