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How to screen out the key variables from massive observed and control variables for modeling the dioxin emission has become an important issue in incinerator operation and pollution prevention.
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These findings identified elevated temperatures as the principal cause of the observed massive reductions in leaf density and canopy cover and supported the hypothesis that mild anthropogenic warming could exceed the thermal thresholds of many southern African quartz field succulents leading to metabolic impairment.
Neither their localization nor distribution nor abundance could explain the observed massive pyramidal cell-death.
The observed massive reductions in ATP level (Fig. 1a) as well as the EC index (Fig. 1d) were remarkably greater than in the other hippocampal regions.
This is supported by a number biochemical studies that observed massive generation of ROS and the insufficiency in antioxidant capacity in asthma [ 65– 65].
Our discovery that HDAC activity was involved in photoreceptor degeneration may thus help to close a major gap of knowledge between the immediate effects of a single gene mutation and the observed massive changes at the transcriptional level.
These rearrangements in fatty acid metabolism indicate an alteration of types and sites of lipid synthesis due to changed lipid demands and explain the often observed massive lipogenesis under N-limitation in E. huxleyi.
This transcriptional regulator is known to activate transcription of genes encoding ribosomal proteins [ 25, 26] and its downregulation is consistent with the observed massive decrease in transcripts for ribosomal proteins.
18, 19 Overall, we find it likely that the massive increase in observed survival in prostate cancer patients to a greater degree reflects a change in the patient population than a real improvement in survival.
Various transcription and splicing factors were found to be either up-regulated or down-regulated in the arthritogenic SF clone, in accord with the observed massive reprogramming of gene expression.
Down-regulation of pathways enriched for Oxidative Phosphorylation, citrate cycle, and fatty acid metabolism suggested an energy crisis with massive mitochondrial dysfunction, supporting the observed necrosis in the cardiac histopathology.
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