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These previously unsuspected massive modifications of Earth's past environments are, of necessity, reflected in the evolutionary history of life.
Any car will be fun for the week, most stock vehicles have no trouble surviving our rigors, but to be in the top 10 requires, for most cars, massive modifications, and the cars must be built to endure.
The last two generations have been the frame of massive modifications in life and food habits, with people being more and more sedentary, overfed and permeated with drugs and pollutants.
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To not do so would be a massive modification of the original data.
An increase in fluorescein and FITC-dextrans (4 kDa/70 kDa) permeability was also observed, which can be related to a substantial opening of endothelial cell tight-junctions but without massive modification of tight-junction protein (ZO-1, ZO-2, claudin-5, occludin) immunolabeling even 8 days after 25 Gy exposure.
These results demonstrates for the first time that learning an operant conditioning task requires while learning massive modification of the neural circuits, whereas when the task is already learned, process decreases and is more related to late establishing of the neural circuitry.
Grafting induces massive transcriptional modifications in the shoot apical meristem of the grape scion.
Massive infrastructure modifications were necessary to achieve the desired objectives of increased capacity to triage and treat seriously ill patients and at the same time protect healthcare workers.
During these stages, spermatids undergo massive morphological modifications such as acquisition of cell polarity, condensation of chromatin, formation of the acrosome and tail, and production and elimination of the residual body.
"Treasury had failed to ensure that the servicers had the necessary infrastructure to support a massive mortgage modification program".
The resulting massive gene dosage modifications could explain their predisposition to acquire paclitaxel resistance.
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