These tissue reactions included graft rejection, massive infiltration of inflammatory immune cells, and gliosis.
Glioblastoma multiforme (GBM) is among the most aggressive cancers associated with massive infiltration of peritumoral parenchyma by migrating tumor cells.
Subcutaneous implantation of SDF-1α-releasing gels in mice resulted in massive infiltration of early EPCs and subsequently improved vascularization.
The disease is characterized by a massive infiltration of lymphocytes, mainly T cells, which chronically destructs the epithelium basal layer resulting in an abnormal epithelial keratinization cycle.
(D) Masson's stained section revealed a massive infiltration of cells through the entire CSCL' thickness coming from the surrounding vasculature (inset).
At the ulceration stage, the integrity of the epithelium disintegrates and ulceration occurs with a massive infiltration of leukocytes in response to both tissue injury and secondary microbial infection.
For inflammation: 0, no inflammation; 1, slight inflammation with a few lymphatic and plasma cells; 2, moderate inflammation with higher levels of lymphocytes, plasma cells, eosinophils, and neutrophils; and 3, severe inflammation with massive infiltration of inflammatory cells.
These tumors showed massive infiltration of different organs, starry sky patterns and numerous mitotic figures.
A massive infiltration of inflammatory cells was also detected in the lamina propria of the gastric tissue of AID−/− mice.
The loss of functional pancreatic parenchyma, which is substituted by a fibrotic scar with massive infiltration of lymphocytes, is characteristic of chronic pancreatitis pathobiology.
Histology of the joint sections of CIA mice vaccinated with PBS (Fig. 2A) or MBP (Fig. 2B) showed extensive cartilage and bone erosions with massive infiltration of cells.
