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In this regard, DNA vaccines represent an inexpensive alternative to subunit vaccine for mass vaccination programs designed to induce such responses to human immunodeficiency virus type I (HIV-1).
These findings suggests that it might be possible to eradicate the more slowly evolving influenza B Yamagata virus through mass vaccination programs using existing vaccines.
Following the largest voluntary mass vaccination campaign since the mass vaccination programs with Salk and Sabin polio vaccines, nearly 25% of the US population, or 45 million persons, were vaccinated by October, 10 short months after the alarm was sounded.
So in the case of Ebola, one approach we are currently considering has the potential to plug the funding gap that exists in the scaling-up of vaccine production, which would be necessary both for mass vaccination programs and stockpiling.
In conclusion, the development of new DTPw-based combination vaccines is essential for the success of current and future childhood mass vaccination programs in countries where resources are limited.
As early as 1803, the Spanish Crown organized a mission (the Balmis expedition) to transport the vaccine to the Spanish colonies in the Americas and the Philippines, and establish mass vaccination programs there.
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Conjugate vaccines also induce herd protection by decreasing the carriage rate in vaccine recipients, which was demonstrated in the UK after a mass vaccination program with conjugate serogroup C vaccines [ 19].
This paper identifies the socioeconomic factors associated with vaccine uptake in a mass vaccination program.
If the availability of the first vaccine batches is delayed of 1 month, the mass vaccination program would have almost no mitigation effect (<2%) for all countries under study in the whole range of scenarios explored.
During the study period a mass vaccination program took place in Matlab [ 35- 37]; the cholera vaccine appears to provide temporal immunity and reports suggest that herd immunity was present at some spatial scales [ 38- 40].
But public-health experts maintain that a mass vaccination program is unwise.
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