The plasma concentration of the dexamethasone was determined using liquid chromatography tandem mass spectroscopy (LC-MS/MS System, AB SCIEX, Framingham, MA) at each time point.
The alkylated product prepared, separated, and collected as described above was analyzed by mass spectroscopy using a chromatographic system consisting of an Agilent 1200 series HPLC system, including a binary pump (Model G1312B), a vacuum degasser (Model G1379B), an autosampler (Model G1367C), and a column oven (Model G1316B).
Substrate surface morphology variations after anodization and the residual gas mass spectroscopy of the experimental system.
Tumor DNA was extracted from FFPE tissue and screened for hotspot mutations in CTNNB1 using a combination of multiplexed primer extension assays and a mass spectroscopy readout (Sequenom MASSArray system) as previously described 20 (Supporting Information).
The components of the complexes can be identified by mass spectroscopy, yeast two-hybrid systems and other related methods (Gavin et al., 2006; Krogan et al., 2006) and their structures can be solved by X-ray crystallography (Dutta and Berman, 2005).
The Chemical Analysis segment manufactures gas chromatography mass spectrometry systems, inductively coupled plasma mass spectrometry instruments, atomic absorption instruments, inductively coupled plasma optical emission spectrometry instruments, molecular spectroscopy instruments, vacuum pumps, and measurement technologies supports and services.
For the samples collected in 2004 and 2005, the As metabolites were speciated using HPLC-HG-inductively coupled plasma mass spectroscopy (ICPMS) (Agilent 1100 series system and Agilent 7500ce; Agilent Technologies, Waldbronn, Germany) (Lindberg et al. 2006).
The exceptional performance of ultrahigh-resolution FTICR mass spectroscopy in the characterization of complex systems suffers much less from the detrimental effects of intrinsic averaging, which is a characteristic of most other methods of organic structural spectroscopy.
The SNPs were tested by using the Sequenom genotyping platform (Sequenom®, San Diego, CA, USA), which uses MALDI-TOF mass spectroscopy and MassARRAY technology with an iPlex system.
The tryptic digest was analyzed by capillary liquid chromatography tandem mass spectroscopy (LC-MS/MS) using Water's CapLC/QTOF2 system.
