Metabolomic analysis was performed using 3 liquid chromatographies coupled to high resolution mass spectrometry methods (LC-HRMS).
Metabolomics allows a relatively complete snapshot of metabolic processes in a sample using different mass spectrometry methods.
Akos Vertes, professor of chemistry at George Washington University in Washington, DC, uses mass spectrometry methods to quantify metabolites at the single-cell level.
Moreover, reported chromatography and mass spectrometry methods identified elevated urine formaldehyde levels in patients with bladder cancer, dementia, and early stages of cognitive impairments compared to healthy people.
After PIns was purified, the homogeneity of it was characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis, isoelectronic focusing electrophoresis, amino acid composition analysis and mass spectrometry methods.
Advanced nuclear magnetic resonance (NMR) and mass spectrometry methods enable the quantitative assessment of all major isotopologue species present in metabolites recovered from isotope incorporation experiments.
We identified and characterized the isomerization site using ion-pair reversed-phase HPLC mass spectrometry methods of the reduced and alkylated antibody and the enzymatically cleaved antibody.
Drug testing in hair usually requires a rather complex sample treatment before drugs are amenable to analysis by either immunological and/or chromatographic coupled to mass spectrometry methods.
Sharon went to work at the University of Cambridge in the lab of Carol Robinson (now at the University of Oxford), who had pioneered new structural mass spectrometry methods that made it possible to study huge protein complexes.
The main advantage of NMR spectroscopy, as well as the sample preparation, is that it is not discriminatory, unlike certain mass spectrometry methods that rely on the prior separation and/or derivatization of metabolites.
Here, the single curves represent the distributions obtained with the in situ mass spectrometry methods (before the selection by mass), and the shadowed regions represent the distributions obtained by HAADF.
