Sentence examples for mass reduction model from inspiring English sources

The 4/6 renal mass reduction model is used as a milder variant since it does not induce hypertension, and only moderate renal dysfunction and glomerulosclerosis [ 29, 30].

This study aimed to elucidate if the 5/6 renal mass reduction model is a good model for the Wnt/ β-catenin activation and possible next modulation.

Wnt/ β-catenin activity was assessed during the development of fibrotic remodeling in the rat 5/6 renal mass reduction model.

This study aimed to elucidate if the rat 5/6 renal mass reduction model (RMR) is a good model for the Wnt/ β -catenin activation and possible next modulation.

To do this, we used 5/6 renal mass reduction model animals and we sacrificed animals at 12 and 18 weeks after the surgery, when CKD is well established, and then we characterized the fibrosis establishment and the Wnt activation.

In a prevention-type study, remarkable reductions in proteinuria and glomerulosclerosis were observed after selective blockade of ETA receptors in a rat renal mass reduction model of hypertensive glomerular disease [ 86].

As previously observed for other WAT mass reduction models, the circulating level of leptin, secreted by white adipocytes, was significantly reduced in mice treated with D-WAT.

The modelling results suggest that short term benefits are obtained and related to mass reduction at the sites where the model was tested.

In summary, sitagliptin treatment attenuated renal dysfunction and structural damage in a model of renal mass reduction.

More recently, Ang-(1 7) infusion has also been shown to increase relative mesangial area in a mouse model of renal mass reduction induced by 5/6 STNx [ 17].

In the experimental model of renal mass reduction by five-sixths nephrectomy, resembling advanced phases of CKD, the remnant glomeruli undergo hypertrophy, and the tone of afferent arterioles drops more than that of efferent arterioles [ 5].