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Heritability of adiponectin was 33.2% (P <.01), and age, sex, and body mass index explained 23.4% of the variance in adiponectin.
46 The fact that unhealthy behaviours and body mass index explained up to 45% of the socioeconomic gradient in type 2 diabetes in this population in early old age has important public health implications.
For example, the British Regional Heart Study (a cohort of over 7000 men between 40 and 59 years of age recruited in 1978 80) found that variation in systolic blood pressure explained 27% of geographical variation in CHD incidence in Great Britain, body mass index explained 6%, and serum cholesterol levels had no affect.
11 Health behaviours and body mass index explained about a third of socioeconomic differences in incidence of type 2 diabetes when assessed at baseline this is consistent with previous reports on this and other cohorts 102122 butup up to 45% when we accounted simultaneously for changes over time and long term exposure.
We found that health behaviours and body mass index explained 33% of socioeconomic differences in incidence of diabetes when they were assessed at study baseline, 36% when assessed repeatedly over the follow-up, and 45% when we additionally accounted for long term exposure.
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Health behaviours and body mass index explain almost half of the association between socioeconomic status and incidence of type 2 diabetes.
A formula developed using a multiple regression analysis, and taking into account muscle mass assessed by BIA, as well as sex and body mass index, explains 89% of the ALM/ht assessed by DXA.
"Taking into account multiple outcomes [such as residential density, land use mix, and commuting time] will likely help to explain the variation within individual outcome measures such as body mass index," Frank explained.
Adjustment for adult concurrent body mass index fully explained the associations of maternal prepregnancy body mass index with cardio-metabolic risk factors in adulthood.
Childhood body mass index fully explained the associations of first trimester fetal crown to rump length with childhood total fat mass.
Although maternal pre-pregnancy body mass index partly explained the ethnic differences, the odds ratio (OR) of being overweight remained higher in the Turkish (OR: 2.66; 95%CI: 1.56-4.53) and Moroccan (OR: 2.11; 95%CI: 1.31-3.38) groups after adjusting for prenatal factors.
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