Sentence examples for mass difference to from inspiring English sources
As a baseline method to evaluate against, we use the naïve method that returns the molecular formula with the smallest mass difference to the measured parent mass.
The nonlabeled and labeled counterparts coelute during RP-HPLC separation but exhibit a sufficient mass difference to be distinguished by MS detection.
If we restrict our search to molecular formulas that are contained in PubChem, and again rank molecular formula candidates by mass difference to the measured parent mass, we find the correct molecular formula for 17.1 % of the instances in top rank, and 59.8 % in the top 5.
If we examine the ratios of the peaks d, e and f, assigned on the basis of mass difference to loss of U1-C, we find the same pattern of splitting as peaks for the intact particle (a, b and c) the central peak being predominant consistent with sub-complexes containing the same ratio of different isoforms as the intact complexes (figure 1).
We conclude that in HEK293 cells propeptide cleavage does not occur resulting in the observed molecular mass difference to the native protein, which accounts for the propeptide fragment.
Manual inspection of the mass spectra corresponding to the SNPs was carried out and through the clear presence of y ion series (as shown in Figure 7), we attributed the mass difference to amino acid change and eliminated the possibility of post-translational and other modifications.
Decreasing the initial energy E 0, the backscattering cross section is increased that can dedicate better mass differences to target atoms in the sample.
We then merge peaks from fragmentation spectra with different collision energies with mass difference up to 10 mDa [41]: in this case, we use the mass of the highest peak, and sum up intensities.
After derivatization, control and knockdown samples were mixed equally; they could be distinguished because of a mass difference corresponding to a 5 Da shift.
Next, we constructed a mass difference matrix to identify relationships between any two detected masses, whereby an "exact" difference of one monosaccharide (hexose/Hex, N-acetylhexosamine/HexNAc, deoxyhexose/dHex, sialic acid/Sia) was considered a match.
When a mass difference corresponding to a known PTM was observed, rules were applied that examine the sequence of the peptide of interest and make predictions as to which amino acid in the peptide was likely to carry the modification.
