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The aim of this study was to (a) examine the association between upper leg lean tissue mass, knee extensor strength, muscle quality (strength per unit lean tissue mass) and functional performance and (b) to determine the utility of tertiles of muscle strength and muscle quality to distinguish gradations of functional capacity in healthy 50 70 y women.
According to Wolfe et al, 15 a total of 1.5 g/ kg/day can increase muscle mass and functional fitness.
The reduction in testes size correlates strongly with the reduction in testosterone, muscle mass and functional strength.
Cachectic Apc Min/+ mice exhibit a reduction in circulating testosterone and gonad size, which has a significant association with the degree of muscle mass and functional strength loss.
In addition, the loss of autonomy is associated with a decrease in physical activity leading to reduced muscle mass and functional decline which predispose the elderly to falls.
Although community-based, well-rounded exercise programs have been proven to improve muscle mass and functional fitness, their efficacy in reversing sarcopenia has not been documented.
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To assess relationships between low skeletal muscle mass (SMM) and functional decline in community-dwelling elderly women.
X-ray crystallography, mass spectrometry, and functional data demonstrate that these peptide mimetics are efficient covalent inhibitors of Siah and antagonize Siah-dependent regulation of Erk and Hif signaling in the cell.
A one-way analysis of variance (ANOVA) was used to evaluate potential group differences in baseline characteristics (age, gender, height, body mass index and functional capacity).
In future mass spectrometry and functional studies we hope to explore such possible alternative models as well as identify the cellular target(s) of the FAST2 domain.
Identification using mass spectrometry and functional categorisation of the differentially regulated proteins did not show that any functional category, metabolic pathway or subcellular localization was over- or under represented within non-additive polypeptides [ 24].
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