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Solutions proposed for solving this issue (structure masking, use of surrogate information) [28-30] failed to provide a satisfactory answer to the problem.
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Conservation masking used settings and alignments from Edwards et al.
For sequence cleaning, adapter-ligated sequences were masked using SSAHA2 [ 82], and undesirable sequences (such as mitochondrial DNA, rDNA or contaminant-derived) identified for masking using BLAST2 [ 83].
Mask use did not affect task performance.
Error tended to increase with increased mask use.
Thirty-eight (75%) patients from the intervention arm reported discomfort with mask use (Table 4).
Mask use adherence was self-reported.
Ninety-five physicians responded to the questionnaire on mask use.
Mask use, complications, and tolerance were also assessed.
Table 3 shows reported problems with mask use.
Apparently no controlled studies assess the efficacy of mask use in preventing transmission of influenza viruses.
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