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DTCs in bone marrow were identified using monoclonal antibodies against cytokeratins for detection of epithelial cells.
In a panel of 38 colorectal cancer patients, EMMPRIN-positive tumour cells in the bone marrow were identified in 11 cases, and interestingly, EMMPRIN-expressing cells were found in four of five patients with synchronous metastases (Buergy et al, 2009).
Most findings of DC ontogenesis occurred about 20 y ago when the culture conditions to efficiently generate ex vivo large numbers of dendritic cells from mouse bone marrow were identified.
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The active contour model was developed in a MATLAB (MathWorks Inc., Natick, MA, USA) environment and was applied to CT1, where the LV bone contour (enclosing compact bone and bone marrow) was identified, providing a CT image of the compact bone and bone marrow (CT2).
Not surprisingly, bone marrow was identified as being highly enriched for bone.
AcSDKP isolated from bone marrow was identified as a physiological regulator of cell proliferation [ 9].
The tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) isolated from bone marrow was identified as a physiological regulator of hematopoietic stem cell proliferation [ 9].
Circulating endothelial progenitor cell (CPC), mainly derived from the bone marrow, is identified by the surface expression of CD34 and CD133 epitopes (CD34+CD133+ cells) [ 1].
While T and B cell development was very low in the Rag2−/−γc−/− mice, higher numbers of lymphocytes (but still lower than would be expected in bone marrow transplants) were identified in the immunocompetent mice.
Thymocytes generated either from Pak2 +/+ or Pak2 F/F ;Cd4- Cre donor bone marrow cells were identified using CD45 congenic markers and CD4 vs CD8 expression was shown.
Laboratory tests during the 30-days post-bone marrow biopsy were identified and patients followed for up to 1 year post-index.
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