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Molecular relapse had to be confirmed by nested RT PCR in two marrow samples taken 2 to 4 weeks apart.
Immunophenotypic analysis was carried out using bone marrow samples taken at diagnosis and analyzed in the reference laboratory by standard immunofluorescence methods.
Interestingly, these cells were generated at a higher rate from bone marrow samples taken from RA patients, compared with normal subjects.
Within the ALL bone marrow samples taken at initial diagnosis, the S phase was not related to white blood cell count, age, or gender.
A total of 74 bone marrow samples from human leukemia patients and 15 bone marrow samples taken as normal controls were collected from Changhai Hospital in Shanghai with written consent.
PolySia-NCAM-positive tumor cell clusters, as shown in Figure 3, were found in two different bone marrow samples, taken at different time points from the same patient with a polySia-NCAM positive primary tumor.
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Patients in group II had one bone marrow sample taken yearly.
The researchers used an off-the-shelf microarray made by Affymetrix, a company that pioneered the biochip, to analyse bone-marrow samples taken from 38 patients with two similar forms of leukaemia, one called acute lymphoblastic leukaemia (ALL) and the other acute myeloid leukaemia (AML).
We sequenced the bone-marrow samples taken from a patient with B-cell acute lymphoblastic leukemia (B-ALL) showing a TR γ rearrangement.
Bone-marrow samples taken from a patient at diagnosis and after treatment were obtained from the tissue bank "Tumorothèque du Centre de Référence Régional en Cancérologie de Lille (CRRC)" which certified cell cryopreservation quality.
The aspirin doesn't help, so she finally asks for some blood tests and soon she winds up at Massachusetts General Hospital, in Boston, where a young and talented physician gives her the preliminary diagnosis: acute lymphoblastic leukemia (A.L.L .. Carla knows nothing about lymphoblasts, or why she's going to have to have a bone-marrow sample taken, but she knows about leukemia.
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