Sentence examples for marrow microenvironment is a from inspiring English sources
The regulation of erythropoiesis in the bone marrow microenvironment is a carefully orchestrated process that is dependent upon both systemic and local cues.
The MM bone marrow microenvironment is a hypoxic niche.
However, the effect of MM on MSC number in the bone marrow microenvironment is a current area of controversy.
The bone marrow microenvironment is a secluded and potentially safe body niche, in which cancer cells can be protected against chemotoxic agents.
Thus, the intercellular communication of HSPCs with their bone marrow microenvironment is a novel research field that requires further investigation (Méndez-Ferrer et al, 2010) and the development of animal models to demonstrate its in vivo impact.
Interestingly, bone marrow microenvironment is also a critical reservoir for DTCs.
The bone marrow microenvironment is vital to the development, differentiation, and regulation of the lymphohematopoietic system.
The bone marrow microenvironment is also hypoxic in MM patients.
Furthermore, there is increasing evidence that, in certain hematological disorders, the marrow microenvironment is abnormal, both in composition and function [ 10].
The bone marrow microenvironment is composed of many cellular and cellular components such as endothelial cells, stromal cells, osteoclasts, osteoblast, immune cells, fat cells, and extracellular matrices.
Similar to the situation in patients, Ewing tumours metastasise at high frequency to bone and bone marrow in NOD/ scid mice (Vormoor et al, 2001), indicating that the bone marrow microenvironment is supportive for growth and survival of these cells.
