Sentence examples for marrow microenvironment is from inspiring English sources

The bone marrow microenvironment is vital to the development, differentiation, and regulation of the lymphohematopoietic system.

The regulation of erythropoiesis in the bone marrow microenvironment is a carefully orchestrated process that is dependent upon both systemic and local cues.

Interestingly, bone marrow microenvironment is also a critical reservoir for DTCs.

The bone marrow microenvironment is also hypoxic in MM patients.

The MM bone marrow microenvironment is a hypoxic niche.

However, the effect of MM on MSC number in the bone marrow microenvironment is a current area of controversy.

Compounds designed to block the identified cellular interactions within the bone marrow microenvironment are expected to mobilise the leukemic cells and make them more accessible to contemporary antileukemic agents.

The importance of ARTEMIS in primary MSC derived from the bone marrow microenvironment was tested in detail using knockout mice [ 26].

Whereas the main producers of IL-6 in the bone marrow microenvironment are most likely the bone marrow stromal cells, some MM cell lines both produce and respond to IL-6, supporting an autocrine proliferation loop.

Interactions between myeloma cells and cells of the bone marrow microenvironment are critical for myeloma growth and survival and for the development of the osteolytic bone disease [ 13, 14].

Lymphodepletion due to the altered bone marrow microenvironment was observed in the ApcMin/+ mouse model of intestinal tumorigenesis [ 15], which indicates the lymphodepletion may contribute to the drop of anti-tumor immune and tumorigenesis.