To determine a gene signature for hematopoietic progenitor and stem cells, we used the datasets derived from 57 CD34+ sets, as whole bone marrow sets may not be a true reflection of these progenitors, being as they are a mixture of various cell types.
MPR regimen may be preferred for patients with pre-existing neuropathy, whereas patients with limited bone marrow reserve may not be suitable for this regimen.
Finally, although bone marrow examination may not be recommended for the majority of patients presenting with features characteristic of ITP [ 1], the judicious performance of this procedure may be necessary in patients with atypical features, particularly in the elderly.
This has important implications for our understanding of this disease, as it suggests that there is an early metabolic transformation of the bone marrow microenvironment that may not be dependent on significant plasma cell occupancy, and that the progression of the disease to MM requires changes to the metabolic phenotype that are not necessarily visible in this niche.
However, the change in v e.BM among the three groups was nonsignificant, indicating that the marrow fat content change may not be the main contribution to the perfusion function degeneration in osteoporosis.
This is because of the balance between any possible effects on tumour metabolism (such as macrophage impairment) and systemic effects (such as bone marrow activation following bone marrow depression, which may or may not be caused by growth factors).
This is because of any possible effects on tumour metabolism (such as macrophage impairment) and systemic effects (such as bone marrow activation following bone marrow depression, which may or may not be caused by growth factors).
Diffuse bone marrow involvement, which may or may not be associated with bone destruction, is not evaluable using conventional radiography.
This finding suggests that the amount of memory NK cells might be extremely low in blood or bone marrow samples, or that CD45RO may not be a marker of memory NK cells.
Testicular tumours that cause alopecia are not always associated with feminisation or increased concentration of oestradiol in dogs [ 9, 38], and even in cases of bone marrow suppression, clinical signs of feminisation may not be noticed by the owner [ 15].
