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Tumour (asterisk) with marrow invasion and extensive infiltration of the floor of the mouth (dashed arrow).
Decreasing extent of marrow invasion, reduction of tumour volume and a decrease in the amount of associated oedema are favourable conventional MRI indicators (Fig. 25).
Several authors reported a normal bone marrow MR signal in patients with leukaemia, in patients with early stages of bone marrow invasion by lymphoproliferative diseases and even in up to one-quarter of patients with stage III MM [24, 33].
A thin-section (3 mm), small field of view (FOV) (16 18 cm), fast spin echo, T1-weighted sequence is best to depict bone marrow invasion and assess fat planes at the skull base.
Published toxicity (MAX2), diastolic blood pressure, marrow invasion and lactate dehydrogenase (LDH) were all associated with toxicity (P<0.1); Body Mass Index, previous chemotherapy, red blood cells, platelets, polymedication with dose-intensity; and polymedication with FACT-G change.
Twenty-four had bone marrow invasion.
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However, the relationship between the inflammatory reactions of TNF- α or IL-6 and bone marrow cell invasion awaits clarification.
However, the relationship between the inflammatory reactions of TNF- α or IL-6 and bone marrow cell invasion has not been fully clarified.
Functionally, antibody blocking of CD164 prevents the binding and migration of prostate cancer cells to bone marrow endothelium and invasion via the extracellular matrix.
Despite these aggressive features, both marrow and CNS invasion are uncommon in pediatric ALCL, occurring in <10% and <5% of cases, respectively.
In addition, Abraham et al. [25] have reported CD44+/CD24− metastatic breast cancer cells in the bone marrow possessing high invasion ability.
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